Personalized cancer vaccines are having a moment

Vaccines targeting some of our deadliest cancers are showing promise in early trials. KEY TAKEAWAYS By Kristin Houser Promising personalized cancer vaccines were a recurring theme at the American Association for Cancer Research’s (AACR) Annual Meeting in San Diego, earlier this month. A multitude of companies are pushing forward with shots designed to help the immune system fight patients’ specific tumors. Personalized cancer vaccines: Cancer cells are covered in mutated proteins, called “neoantigens,” that are not found on healthy cells. Personalized cancer vaccines train the immune system to recognize a patient’s unique neoantigens and then find and destroy the cancer cells. Because researchers … Continue reading Personalized cancer vaccines are having a moment

Clarence Thomas’ 38 Vacations: The Other Billionaires Who Have Treated the Supreme Court Justice to Luxury Travel

Alex Bandoni/ProPublica. Source Images: mikroman6 and Bloomberg/Getty Images. by Brett Murphy and Alex Mierjeski The fullest accounting yet shows how Thomas has secretly reaped the benefits from a network of wealthy and well-connected patrons that is far more extensive than previously understood.    ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. During his three decades on the Supreme Court, Clarence Thomas has enjoyed steady access to a lifestyle most Americans can only imagine. A cadre of industry titans and ultrawealthy executives have treated him to far-flung vacations aboard their yachts, ushered … Continue reading Clarence Thomas’ 38 Vacations: The Other Billionaires Who Have Treated the Supreme Court Justice to Luxury Travel

Read how much Trump paid — or didn’t pay — in taxes each year

Former U.S. President Donald Trump speaks at a rally for Sen. Marco Rubio (R-FL) at the Miami-Dade Country Fair and Exposition on November 6, 2022 in Miami, Florida. Joe Raedle | Getty Images By Dan Mangan KEY POINTS The amount of income, deductions and taxes paid by or refunded to former President Donald Trump while serving in the White House was detailed in a new report released Tuesday night. The report reveals that Trump on his federal tax returns declared negative income in 2015, 2016, 2017 and 2020, and that he paid a total of $1,500 in income taxes for the years 2016 and … Continue reading Read how much Trump paid — or didn’t pay — in taxes each year

Trenches in Chernobyl

An abandoned Russian trench near a military post in the Chernobyl exclusion zone in Ukraine, 13 September 2022. Photo by Narciso Contreras/Anadolu Agency via Getty Disturbing and inhaling radioactive dust, in their haste Russian soldiers unburied the wrecked, undead Earth itself Michael Marder is Ikerbasque Research Professor of Philosophy at the University of the Basque Country in Vitoria-Gasteiz, northern Spain. His books include Green Mass (2021), Philosophy for Passengers (2022) and The Phoenix Complex: A Philosophy of Nature (forthcoming, 2023). Contemporary events appear in ever-shifting configurations. They seem to be entirely contingent, their amplification on the global scale dependent on how many people are paying attention. The … Continue reading Trenches in Chernobyl

How It Feels to Surf the World’s Biggest Wave

Riding Earth’s mighty forces in Nazaré, Portugal. BY KRISTEN FRENCH When you first see the leviathan arch of the world’s biggest wave tower over the cliffs of Nazaré, Portugal, its crown of angry froth exploding onto itself, you might wonder if it isn’t the tongue of God come to swallow the Earth. Surging vertically to a height of up to 100 feet just behind an ancient lighthouse, the wave has all the menace of a massive tsunami, but unlike a tsunami, it can be surfed. When conditions at Nazaré are right, in the months between October and March, modern-day Prometheans … Continue reading How It Feels to Surf the World’s Biggest Wave

‘Dangerous’: Greenpeace slam Saudi Arabia ski resort as Kingdom wins 2029 Asian winter games bid

By Charlotte Elton  Campaign group Greenpeace has slammed a “dangerous” ski resort being built in Saudi Arabia. The warning comes days after the desert kingdom won its bid to host the 2029 Asian Winter Games. Saudi authorities claim that the new Trojena resort in the country’s north west will operate on “sustainable infrastructure” and renewable energy. But Greenpeace campaigners have questioned the project’s environmental credentials. “You’re changing a natural ecosystem which can have compounding impacts,” says Ahmed El Droubi, regional campaigns manager for Greenpeace. “If you change something in one place, it may change something else in another place, and so on, and it can have impacts … Continue reading ‘Dangerous’: Greenpeace slam Saudi Arabia ski resort as Kingdom wins 2029 Asian winter games bid

Forget Skyscrapers: Dubai Architecture Firm Proposes a Sky Circle

ZN | Era’s Downtown Circle would surround the Burj Khalifa By Rain Noe  From Dubai-based architecture firm ZN | Era comes this interesting proposal: The Downtown Circle, a massive elevated circular structure that would surround the Burj Khalifa. (Think supersized version of Apple’s headquarters, in a configuration ill-suited for acrophobes.) “As a response to the dilemma of how to build densely while retaining liveability, the Downtown Circle project establishes a sustainable and a self-sufficient vertical urbanism. As a singular mega building complex, it aims to create a hyper efficient urban center that gives back to the environment. The proposed 550 meter … Continue reading Forget Skyscrapers: Dubai Architecture Firm Proposes a Sky Circle

Shocking Photos Show Western ‘Fast Fashion’ That Pollute African Beaches

 by MATT GROWCOOT Photographer Muntaka Chasant has documented thousands of washed-up clothes on a beach in Africa, laying bare the environmental impact of fast fashion. Chasant tells Petapixel that he took a “beating” from the waves in Ghana to capture the powerful and thought-provoking photographs. “I had to step in the water to capture most of the scenes which gave me a thrashing,” explains Chasant. “Documenting discarded unwanted clothes is part of my long-term focus on the geographies of waste — to highlight the environmental cost and burden of fast fashion.” The disturbing pictures taken in the Ghanaian capital city of Accra, show huge … Continue reading Shocking Photos Show Western ‘Fast Fashion’ That Pollute African Beaches

You Eat a Credit Card’s Worth of Plastic Every Week

What is our hidden consumption of microplastics doing to our health? BY KATHARINE GAMMON Martin Wagner was annoyed that his colleagues were always talking about microplastics in the ocean. It was 2010 and the Great Pacific Garbage Patch had been headline news. Here was this massive gyre, formed by circular ocean currents in the Pacific Ocean, reportedly brimming with plastic particles, killing sea turtles and seagulls. Wagner, a professor of biology at the Norwegian University of Science and Technology, whose lab focuses on the impact of plastics on human and ecosystem health, felt like scientists were pointing to marine systems … Continue reading You Eat a Credit Card’s Worth of Plastic Every Week

The Canary Islands and the Tsunami Threat

The Canary Islands and the Tsunami Threat I. G. Kenyon The Canary Islands comprise 7 volcanic islands that rise 6 to 8 km from the seafloor Eruptions occur on average every 30 years Landslide History of the Canary Islands 1 At least 14 large landslides have been mapped offshore from the Canary Islands Most of these landslides have been dated within the last 1 million years Landslide History of the Canary Islands 2 Recurrence interval is 100, 000 years for all islands and around 300, 000 years for individual islands Landslides comprise 50 to 500 km³ of debris avalanches spread … Continue reading The Canary Islands and the Tsunami Threat